Science,Kids, and Alcohol

 

 

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) funded the research described in the following summary.  NIAAA funds more than 90 percent of the alcohol abuse and addiction (alcoholism) research in the United States.

 

 

Table of Contents 

Suicidal Behaviors and Alcohol Use Among Adolescents: A Developmental Psychopathology Perspective
Continuing Brain Development During Adolescence
Children’s Images of Alcohol
One in Four U.S. Children Is Exposed to Alcohol Abuse and Dependence in the Family Environment
Policy Changes Successfully Reduce Underage Drinking in Typical Communities
Impact of the Minimum Legal Drinking Age 
Why Kids Drink—The Influence of Social Norms
Project Northland—A Communitywide Program to Prevent Underage Drinking
Effect of Heavy Alcohol Use on Nervous System Development in Adolescents
Early Onset of Drinking and Lifetime Alcohol Abuse and Dependence
Effects of Moderate Alcohol Consumption on Brain Function in Adolescents and Adults
Age of Drinking Onset, Driving After Drinking, and Involvement in Alcohol-Related Motor Vehicle Crashes
Using Alcohol Policy to Reduce Underage Drinking: Strategies that Work
The Effects of Lowered Legal Blood Alcohol Limits for Young Drivers
Parental Supervision And Teen Drinking
Drinking and Related Problems: Sex and Race/Ethnicity Age 
Changes in Brain Activity in Alcohol-Dependent Young Women
Enforcement of Underage Drinking Laws: Strategies that Work
Drinking and Domestic Violence

 

Suicidal Behaviors and Alcohol Use Among Adolescents:
A Developmental Psychopathology Perspective

Michael Windle, Ph.D.
Director, Center for the Advancement of Youth Health and the Comprehensive Youth Violence Center
University of Alabama at Birmingham

Suicide is the third leading cause of death among teens in America
.  Each year, one in five American teens seriously considers suicide, approximately one million attempt suicide, and between 1,000 and 2,000 of these attempts are fatal. Suicide is the third leading cause of death among 10- to 19-year-olds, and accounts for more deaths than all natural causes combined. More girls than boys attempt suicide.  However, five times more boys than girls die as a result, probably because boys are more likely to choose a lethal method such as firearms.

Studies have shown that teen suicide is associated with depression, hopelessness, impulsivity, and alcohol and other drug use.  This study explored the contribution of various risk factors, including alcohol use and binge drinking, to suicide attempts. Twelve hundred tenth- and eleventh-graders participated in four waves of data collection over an 18-month period. The study measured motives for drinking, percentage of friends who use alcohol, and binge drinking.  Other risk factors measured included depressive symptoms, temperament (e.g., rigidity, persistence, distractibility), delinquency (e.g., destroyed public property, hit a teacher, was suspended), and stressful life events (e.g., failing one or more subjects, having an acne problem, or breaking up with a boyfriend or girlfriend).  These life events may not seem particularly stressful to adults, but are often magnified in importance by adolescents’ heightened self-consciousness, acute sensitivity to rejection, and emotional fluctuations.

The main results of the study were that a difficult temperament, drinking to cope, low family supports, and a higher percentage of friends who drink predicted current depression, stressful life events, and binge drinking.  These three factors, in turn, predicted suicidal behavior. Of particular importance is that binge drinking was a significant predictor of an actual suicide attempt

  • Suicide is the third leading cause of death among teens in America; each year, one in five American teens seriously considers suicide.
  • Teen suicidal behaviors are influenced by a broad range of factors, with alcohol and other substance use among the prominent influences, along with depressive symptoms, psychosocial factors, and stressful events.
  • Interventions need to be multifaceted, from early detection and treatment of depression, to improving problem-solving and coping skills, to controlling youths' access to firearms.

This and other studies demonstrate that teen suicidal behaviors are influenced by a broad range of factors, with alcohol and other substance use among the prominent influences, along with depressive symptoms, psychosocial factors, and stressful events.  Interventions to address these factors need to be multifaceted, from early detection and treatment of depression, to improving problem-solving and coping skills, to controlling youths’ access to firearms.

Windle M. 2004.  Suicidal behaviors and alcohol use among adolescents: a developmental psychopathology perspective. Alcohol Clin Exp Res 28(5) Supplement:29S-37S.

Continuing Brain 
Development During Adolescence

Ronald E. Dahl, MD

Associate Professor of Psychiatry and Pediatrics

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania

 

Over the past 100-200 years, the age at which puberty begins has been declining, especially among girls. For example, at the beginning of the 20th century the average age of menarche was 16-17 years—it is now occurring on average at age 12.5 years.  The onset of puberty activates new drives, impulses, and emotions as well as changes in motivation.  But some neurobehavioral systems—including frontal brain systems that underpin self-control and mature judgment regarding long-term goals and conse­quences—continue to mature well through late adolescence into early adulthood.  Thus, the drives, impulses, emotions, and changes in motivation that accompany puberty arise before self control and judgment are fully developed.

 

The complex neurobehavioral changes that occur in adolescence interact with the social context of  adolescence in ways that may further increase risk.     While adolescents are typically dealing with increasingly difficult decision-making and challenges to self-control, external constraints on behavior are falling away. For example, the biologic tendency to stay up later that accompanies puberty often interacts with greater self-selection of bedtimes to create severe sleep deprivation for many high school students.  Sleep deprivation, in turn, has a negative impact on the brain systems necessary for mature judgment.

 

Taken together, the early onset of puberty; the appearance of drives, impulses, and emotions before the appearance of self-control and mature judgment; and the decrease in external constraints that attends the beginning of adolescence increase the risk of a number of health problems including alcohol and other drug use.  Approaches to prevention and strategies for early identification of children at risk should consider biological, psychological, and social development as well as the interaction between these factors in determining vulnerability to a variety of health threats.

 

·    Over the past 100-200 years, the age at which puberty begins has been declining, especially among girls.

·    The drives, impulses, and emotions as well as changes in motivation that accompany puberty arise before self-control and judgment are fully developed.

·    The complex neurobehavioral changes that occur in adolescence interact with the social context of  adolescence in ways that may further increase risk.

 

 

This summary was prepared from Dr. Dahl’s presentation at the National Conference of the Leadership initiative, March 2000.  Dr. Dahl is currently supported on NIAAA grant RO1AA12504—Sleep/Arousal in Adolescents: Pathways to Alcohol Abuse.

 

 

 

Children’s Images
of Alcohol

Mark S. Goldman, PhD

Distinguished Research Professor of  Psychology

University of South Florida

Tampa, Florida

 

Information stored in memory prepares people for the circumstances they encounter.  Otherwise, every moment would be an entirely new experience requiring thought and planning.  This type of information is called “expectancies” and is believed  to operate more or less “automatically” — that is, without conscious thought.

 

It is becoming increasingly clear that expectancies play an important role in alcohol use and related problems.  Expectancies about the effects of alcohol are highly related to individual drinking habits. Individuals with strong positive alcohol expectancies drink more and are at greater risk for problem drinking patterns.

 

Children begin to acquire alcohol expectancies at a very young age (perhaps as young as 3 or 4 years old).  In early childhood, alcohol expectancies tend to be negative (e.g., alcohol makes one sick, mean, and argumentative).  However, by fifth and sixth grade, these expectancies turn positive, focusing on the arousing and positive effects of alcohol use (e.g., alcohol makes one social, happy, and sexy).  Thus, alcohol expectancies are largely positive by the time experimentation with alcohol begins.

 

·    Information stored in memory prepares people for the circumstances they encounter.  This type of information is called “expectancies.”

·    Individuals with strong positive alcohol expectancies drink more and are at greater risk for problem drinking patterns.

·    Children begin to acquire alcohol expectancies at a very young age.

 

All children in our culture develop alcohol expectancies whether or not they have had any personal experience with consum­ing alcoholic beverages.   When these expectancies are strong and positive, individuals are more likely to begin drinking early in adoles­cence and to get into difficulties with alcohol use.  Researchers are now studying methods to alter children’s alcohol expectancies and thereby to decrease the risk of early onset of use and abusive drinking.

 

 

Dunn ME, Goldman MS.  1998.  Age and drinking-related differences in the memory organization of alcohol expectancies in 3rd-, 6th-, 9th-, and 12th grade children.  J Consult Clin Psychol 66(3): 579-85.

 

 

 

One in Four U.S.
Children Is Exposed to Alcohol Abuse and
Dependence in the
Family Environment

 

Bridget F. Grant, PhD

Chief of Biometry

Division of Biometry and Epidemiology

National Institute on Alcohol Abuse and Alcoholism

Bethesda, Maryland

 

The harmful effects of alcoholism extend far beyond those experienced by alcoholics themselves.  For example, children in families affected by alcohol often live in environ­ments that are stressful, chaotic, and frightening.  Frequently they are neglected or abused and face economic hardship and social isolation as well.  Studies show that children of alcoholics are vulnerable to mental illness and medical problems and are more likely than others to become alcoholic themselves.

 

In 1992, the National Institute on Alcohol Abuse and Alcoholism conducted the largest national survey on alcohol use ever performed in the U.S. or elsewhere.  This research revealed that almost 14 million U.S. adults meet the criteria for a diagnosis of alcoholism or alcohol abuse.  Given the magnitude of alcohol disorders among U.S. adults and the potential risk they pose for the children in their families, epidemiologists sought to determine how many U.S. residents aged 17 or younger are exposed to alcoholism or alcohol abuse by a family member.

 

Using data from the 1992 survey, epidemiologists recently estimated that more than 28 million U.S. children under 18 (almost 43 percent) lived in households with 1 or more adults who had been alcoholics or alcohol abusers at some time in their lives.  About 10 million of those children (approximately 15 percent) lived in households with an adult diagnosed with alcoholism or alcohol abuse in the past year.  Based on these two figures, it is estimated that 1 in 4 U.S. children (19 million children), before the age of 18, lives in a family with a member who is an alcoholic or abuses alcohol.

 

·    One in four youth, or 19 million kids, is exposed to family alcoholism or alcohol abuse some time before the age of 18.

·    Children in families affected by alcohol often live in environ­ments that are stressful, chaotic, and frightening.

·    Children of alcoholics are vulnerable to mental illness and medical problems and are more likely than others to become alcoholic themselves.

 

Social and health services for children of alcoholics are fragmented and often fail to address the far-reaching effects of familial alcohol exposure. The findings described here illustrate the urgent need to establish a comprehensive strategy for children at risk.

 

 

Grant BF.  2000.  Estimates of US children exposed to alcohol abuse and dependence in the family.  Am J Public Health 90(1): 112-115.

 

 

Policy Changes
Successfully Reduce
Underage Drinking in Typical Communities

 

Alexander C. Wagenaar, PhD

Professor and Director

Alcohol Epidemiology Program

University of Minnesota

Minneapolis, Minnesota

 

Communities Mobilizing for Change on Alcohol (CMCA), a 6-year trial funded by the National Institute on Alcohol Abuse and Alcoholism, was designed to reduce drinking by young people. Rather than using the traditional approach to preventing underage drinking — that is, focusing on the demand for alcohol by young people — CMCA intervened in the supply of alcohol. The study was conducted in 15 small-to-midsize Minnesota and Wisconsin communities.  Seven of the communities were randomly selected for the intervention.  These communities organized to change local policies that affected supply of alcohol to youth and made underage drinking less acceptable in the local culture.  The remaining eight communities served as controls. 

 

Compared with the control communities, CMCA communities had (1) less drinking by 18- to 20-year-olds, (2) reduced sale of alcohol to minors, (3) reduced provision of alcohol to younger adolescents by older adolescents, and (4) more identification-checking by alcohol merchants, who also were less likely to sell to minors.

 

This randomized study shows that typical communities can mobilize to significantly reduce youths’ access to alcohol. The communities involved had paid little attention to issues surrounding youth drinking before they were approached by the researchers.  Thus, the positive outcomes achieved

in the CMCA intervention do not appear to be based on factors that existed in the communities prior to the trial. These findings suggest the potential for other typical communities to achieve similar results.

 

 

·    Rather than focusing on the demand for alcohol by young people, CMCA communities intervened in the supply of alcohol.

·    CMCA communities had (1) less drinking by 18- to 20-year-olds,
(2) reduced sale of alcohol to minors, (3) reduced provision of alcohol to younger adolescents by older adolescents, and (4) more identification-checking by alcohol merchants, who also were less likely to sell to minors.

·    These findings suggest the potential for other typical communities to achieve similar results.

 

 

 

Wagenaar AC, Murray DM, Gehan JP, Wolfson M,

Forster JL, Toomey TL, Perry CL, Jones-Webb R.  2000. Communities mobilizing for change on alcohol:

Outcomes from a randomized community trial.
J Stud Alcohol 61(1): 85-94.

 

 

 

 

Impact of the Minimum Legal Drinking Age

 

Traci L. Toomey, PhD
Assistant Professor of Epidemiology
University of Minnesota,
Minneapolis, Minnesota

 

For most of our Nation’s history, the drinking age was largely ignored as a public policy issue.  During the late 1960s and early 1970s, most States lowered the drinking age in response to public pressure. 

 

When the drinking age was lowered, the number of traffic fatalities among young people increased, prompting concern that young people were traveling between States in order to drink legally.  The legal drinking age came to be viewed as a public health issue rather than as a legal, ceremonial, or symbolic milestone.

 

A limited number of States in the late 1970s and early 1980s raised the minimum legal drinking age (MLDA) to 21.  Studies in these States showed reductions in alcohol-related traffic crashes, a leading indicator of youth drinking.  As a result of this research evidence, the Federal Government passed legislation that would withhold funding unless a State raised the MLDA to 21.

 

Since the 1970s, at least 70 studies have explicitly examined the effects of either increases or decreases in the MLDA.  Rigorous studies typically demonstrated increases in alcohol use among youth following a lowered MLDA. In contrast, when many States raised the MLDA, alcohol use among youth decreased.  A national study also found that the lower rates of alcohol use due to a high legal drinking age continued even after individuals turned 21.

 

Researchers have investigated whether increases in the MLDA affect changes in alcohol-related problems other than traffic crashes.   One study found a 16 percent decrease in rates of van­dalism in four States that raised the MLDA. Another study found lower rates of death from suicides, pedestrian accidents, and other injuries in States with higher MLDA.  Current research estimates suggest that the age 21 MLDA saves the lives of over 1,000 youth each year and prevents countless traffic crashes and injuries.

 

·    Numerous studies have demonstrated that raising the minimum drinking age reduces alcohol consumption and related problems among youth.

·    The positive effects of the age 21 minimum drinking age on youth drinking persist even after individuals turned 21.

·    Consistent enforcement of the minimum drinking age would increase the positive effects of
the law.

 

The dramatic positive effects of the age 21 MLDA have been realized even though these laws are poorly enforced.  For example, studies show that buyers who appear younger than 21 successfully purchase alcohol from licensed estab­lishments without showing age iden­tification in 50 percent or more of their attempts.  Also, although many youth purchase alcohol themselves, most youth indicate that they ob­tain alcohol through friends, siblings, parents, coworkers, and strangers approached outside of alcohol establishments.  It is clear that to  maximize the benefit derived from the MLDA, it must be enforced.

 

Toomey TL, Rosenfeld C, Wagenaar AC. 1996.  Minimum legal drinking age: History, effects, and ongoing debate.  Alcohol Health Res World 20(4): 213-218.


 

 

 

Why Kids Drink—
The Influence of
Social Norms

 

William B. Hansen, PhD
Tanglewood Research, Inc.
Greensboro, North Carolina

 

Social norms are standards or guides that define correct and incorrect behavior in a given situation. Norms embody sentiments that citizens within a given culture hold about what is proper and appropriate.  Although there is no law that says we must shake hands when introduced to someone, most of us do because that is the norm in American culture.  In other cultures this same behavior is considered rude.

 

Norms are reflected in our beliefs about what “most people like us do,” and these beliefs have a strong impact on our behavior.  But what does this all have to do with alcohol use among children and young adolescents?

 

If you ask 6th-graders what proportion of 6th-graders they believe drink, the average answer will be approximately “one-half” — well above the actual figure of 20 percent. Students who overestimate the proportion of drinkers are more likely to drink compared with those students who have correct or low estimates of drinking levels.  In other words, students’ drinking behavior is shaped by their normative beliefs — beliefs that are often wrong.

 

If normative beliefs are important in shaping alcohol use, and if these beliefs are often incorrect and exaggerated, then it follows that we can reduce alcohol use through strategies that correct erroneous normative beliefs. 

 

Consider a program that gathers data on actual alcohol use rates from 7th graders.  These data are then fed back to students and used in debates and discussions about the appropriateness of alcohol use among people their age.  A study of the effects of such a program showed significant reductions in alcohol use, drunkenness, and alcohol-related problems, such as fights, and getting into trouble at home or school.  Youngsters in a comparison group that received instruction in resisting peer pressure increased their alcohol use as if there had been no instruction.  It appears that the pressure to drink is literally inside the young person’s head, stemming from the pressure to conform to normative beliefs about alcohol use.

 

·    The average 6th grader believes that half of his or her peers drink alcohol — well above the actual figure of 20 percent.

·    Students who overestimate the proportion of drinkers are more likely to drink compared with those students who have correct or low estimates of drinking levels.

·    The pressure to drink is literally inside the young person’s head, stemming from the pressure to conform to normative beliefs about alcohol use.

 

As a society, we do a fairly poor job of shaping children’s normative beliefs about alcohol.  When we fail to make our expectations clear, when we tolerate alcohol sales to minors, when we are indifferent to the media messages children receive about drinking, or when we ourselves use or serve alcohol irresponsibly, we contribute to children’s erroneous beliefs about drinking.  Current research is exploring methods for altering normative beliefs about alcohol both in the classroom and in the larger community.

 

Hansen WB, Graham JW.  1991.  Preventing alcohol, marijuana, and cigarette use among adolescents: peer pressure resistance training versus establishing conservative norms.  Prev Med  20(3): 414-430. 

 

Project Northland—

A Communitywide

Program to Prevent
Underage Drinking

 

Carolyn L. Williams, PhD
Professor, Division of Epidemiology School of Public Health
University of Minnesota
Minneapolis, Minnesota

 

Project Northland, funded by the NIAAA, was the largest ongoing community alcohol prevention research project in the United States during the last 10 years.  The project focused on primary prevention of alcohol-related problems using multi­level, multicomponent interventions with both demand and supply reduction strategies for the 6th through 12th grades. 

 

The rationale for the project derived from the premise that underage drinking behaviors are influenced by multiple levels of the social environment (e.g., individual, family, peer group, school, and community).  Thus, a comprehensive intervention is required.  The project’s inter­ventions for early adolescence began during sixth grade and continued through eighth grade.  The interventions included implementation of multiyear school-based prevention curricula, intensive parental involvement, multiple peer leadership opportunities, and community-level changes through the for­mation of task forces. 

 

The initial Project Northland intervention, Slick Tracy, was conducted primarily with parents and young adoles­cents in their homes.  The intervention was presented in four activity books featuring a comic nar­rative about the adventures of teen detectives, Slick Tracy and Breathtest Mahoney, who relayed weekly themes through an adventure.  The program’s four booklets focused on factual information about underage drinking, the influence of role models, peer pressure, and family guidelines.

 

The seventh-grade program, Amazing Alternatives!, was a school-based intervention to develop skills for dealing with peers and to build positive peer group influ­ences.  Amazing Alternatives! included audiotaped stories of young teens, group discus­sions, games, problem-solving exercises, and role plays, many led by peer leaders. The eighth-grade classroom intervention, PowerLines, emphasized influences beyond peers and fam­ilies, empowering young persons to create healthy changes in their broader communities to discourage underage drink­ing, as well as reinforcing skills learned in the previous years. Each intervention year also included a task force working on communitywide changes.

 

·    The rationale for Project Northland derived from the premise that underage drinking behaviors are influenced by multiple levels of the social environment.

·    The project’s interventions included implementation of multiyear school-based prevention curricula, intensive parental involvement, multiple peer leadership opportunities, and community-level changes through the for­mation of task forces.

·    Students who participated in the first 3 years of the project were less likely to begin using alcohol or to have used alcohol in the past week or past month.

 

The effectiveness of the Project Northland interventions was tested with a research design using school districts ran­domized to intervention or control conditions.  Students who participated in the first 3 years of the project were less likely to begin using alcohol or to have used alcohol in the past week or past month.  In addition, Project Northland appeared to be successful in increasing parent-child communication about the conse­quences of drinking, increasing students’ reasons to remain nonusers, reducing peer norms and influences for use, and introducing skills to resist peer influence.

 

 

Williams CL, Perry CL, Farbakhsh K, Veblen-Mortenson S.  1999.  Project Northland: comprehensive alcohol use prevention for young adolescents, their parents, schools, peers, and communities. J Stud Alcohol Suppl 13: 112-124.

 
 
 

Effect of Heavy
Alcohol Use on Nervous System Development
in Adolescents

 

Sandra Brown, PhD
Chief of Psychology Services
VA Medical Center
San Diego, California

 

The immediate effects of intoxication on a person’s ability to think clearly are well known.  But long- term, heavy alcohol use may also have lasting effects on nervous system development in young people.  Recent studies have begun to evaluate the cognitive functioning of alcohol-dependent adolescents.  

 

In one study, cognitive functioning was examined in adolescent subjects recruited from inpatient alcohol and drug abuse treatment centers.  These adolescents had used alcohol heavily during early and middle adolescence when important maturational changes in the nervous system take place.  Matched comparison adolescents who had no history of alcohol or drug disorders were recruited as controls.  The comparisons were similar to the alcohol- dependent teens on key educational, economic, and family factors.

 

The alcohol-dependent and comparison adolescents completed a 2-hour test battery designed to mea­sure verbal and nonverbal learning and memory, perception of spatial relationships, language skills, attention, and problem-solving skills.  In order to allow the dependent adolescents time to detoxify, testing took place in the third week of treatment.

 

The test results revealed subtle to moderate cognitive deficits associated with repeated heavy alcohol use and withdrawal during early to middle adolescence.  Compared with matched controls, alcohol-dependent teens showed impaired memory and altered perception of spatial relationships.  Verbal skill de­ficits were also found in the alcohol-dependent group.  These results, taken with other studies, suggest that problems with cognitive functioning are detectable among adolescents with histories of extensive alcohol use.  These deficits, in turn, may put alcohol-dependent adoles­cents at risk for falling farther behind in school, putting them at an even greater disadvantage relative to nonusers.

 

·    Recent studies have begun to evaluate the cognitive functioning of alcohol-dependent adolescents.

·    Alcohol-dependent teens showed impaired memory, altered perception of spatial relationships, and verbal skill de­ficiencies.

·    The cognitive effects of alcohol may put alcohol-dependent adoles­cents at risk for falling farther behind in school.

 

 

Brown SA, Tapert SF, Granholm E, Delis DC.  2000. Neurocognitive functioning of adolescents: Effects of protracted alcohol use. Alcohol Clin Exp Res 24(2): 164–171.

 

 

 

 

Early Onset of Drinking and Lifetime Alcohol Abuse and Dependence

 

Bridget F. Grant, PhD

Chief of Biometry

Division of Biometry and Epidemiology

National Institute on Alcohol Abuse and Alcoholism

Bethesda, Maryland

 

Much attention has been given to delaying the onset of drinking as a prevention strategy.  Drinking has been associated with a number of serious health problems including dependence.  Other associated problems include tobacco and other drug use, infrequent condom use, early and unwanted pregnancy, exposure to sexually trans­mitted diseases, violence, depression, and suicide. 

 

In 1992, the National Institute on Alcohol Abuse and Alcoholism conducted the largest national survey on alcohol use ever performed in the U.S. or elsewhere.  Data from this survey have extended our knowledge of the relation between age at onset of alcohol use and prevalence of alcohol abuse and dependence in late adolescence and adulthood.  This study was the first to examine effects of early onset of drinking in a large, representative sample of the U.S. population.

 

Lifetime alco­hol dependence (blue line) decreased steeply as a function of increasing age at onset of drinking.  In the total sample, more than 40 percent of respondents who initiated drinking before age 13 were classified with alcohol dependence at some time in their lives.

 

·    Age at first use of alcohol is a powerful predictor of lifetime alcohol abuse and depen­dence.

·    Age at first use is associated with a variety of other health problems including early and unwanted pregnancy, depression, and suicide.

 

By contrast, rates of alcohol dependence among those who started drinking at ages 17 and 18 were 24.5 percent and 16.6 percent, respectively.  The results for lifetime alcohol abuse (red line) were similar to those for dependence, although the decrease with age was less dramatic.

 

These results suggest that preventive efforts should be targeted toward the delay of alcohol use onset.  The weakness of such a preventive strategy is the lack of complete understanding as to why onset of alcohol use is related to the development of alcohol abuse and dependence.

 

Grant BF, Dawson DA.  1997.  Age at onset of alcohol use and its association with DSM-IV alcohol abuse and dependence: Results from the National Longitudinal Alcohol Epidemiologic Survey.  J Subst Abuse 9: 103-110.

 

 

 

 

 

Effects of Moderate
Alcohol Consumption
on Brain Function in Adolescents and Adults

 

Boris Tabakoff, PhD
Professor and Chair
Department of Pharmacology
University of Colorado School of  Medicine
Denver, Colorado

 

Heavy alcohol consumption is associated with a number of neurological and behavioral problems in adolescents and adults.  Here we consider the effects of moderate consumption.

 

Moderate consumption of alcohol affects the function of a variety of brain systems associated with emotion, learning, motivation, and coordination.  These effects can change significantly as blood alcohol content rises and falls during a given drinking episode.

 

Moderate alcohol in­take can produce effects that are pleasurable or motivating.  But people differ in their reactions to alcohol.  The same amount of alcohol can produce positive feelings, increased energy, and reduction of anxiety in some people, but can have an aversive, sedative, incoordinating, or no effect in others.

 

Decreases in the performance of complex cognitive tasks generally occur at blood alcohol levels in the range of those affecting moods and feelings.  Alcohol’s short-term effects on memory occur at higher blood alcohol levels than do effects on performance. It appears that increasing blood alcohol levels first affect mood states, then performance, and then memory. 

 

A num­ber of studies have noted impaired cognitive functioning in people who regularly drink moderate amounts of alcohol.  However, other studies have not found such effects.  Moderate con­sumption of alcohol by pregnant women can have significant negative effects on the developing nervous system of the fetus.  Multiple factors play important roles in determining the effect of alcohol on the developing central nervous system, and different factors may be important in different fetal alcohol effects.   These factors may include gestational period, total alcohol consumption at a particular point during pregnancy, genetic factors, and so on.

 

·    Moderate consumption of alcohol affects the function of a variety of brain systems associated with

·    emotion, learning, motivation, and coordination.

·    The same amount of alcohol can produce positive feelings, increased energy, and reduction of anxiety in some people, but can have an aversive, sedative, uncoordinating, or no effect in others.

·    It appears that increasing blood alcohol levels first affect mood states, then affect performance, and then affect memory.

·    A num­ber of studies have noted impaired cognitive functioning in people who regularly drink moderate amounts of alcohol.  However, other studies have not found such effects.

·    Moderate con­sumption of alcohol by pregnant women can have significant negative effects on the developing nervous system of the fetus.

 

 

Eckardt MJ, File SE, Gessa GL, Grant KA, Guerri C, Hoffman PL, Kalant H, Koob GF, Li TK, Tabakoff B.  1998.  Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res 22(5): 998-1040.

 

This document was supported by the National Highway Traffic Safety Administration, under the Department of Transportation. NHTSA provides a number of resources for the prevention of underage drinking, including the Community How To Guides On Underage Drinking Prevention.

 

Age of Drinking Onset, Driving After Drinking, and Involvement in Alcohol-Related Motor Vehicle Crashes

 

Ralph Hingson, Sc.D.*, T. Heeren, Ph.D.*, S. Levenson, M.Ed., M.P.H.*, A. Jamanka, M.P.H*., and R. Voas, Ph.D.**

*Social and Behavioral Sciences Department

Boston University School of Public Health

Boston, MA

**Pacific Institute for Research and Evaluation

Calverton, MD

 

There is growing evidence that early onset of drinking is a powerful predictor of lifetime alcohol abuse and dependence (see Science, Kids, and Alcohol:  Early Onset of Drinking and Lifetime Alcohol Abuse and Dependence).  The study described here assessed the relationship of early onset of drinking to driving after drinking and involvement in motor vehicle crashes among individuals aged 18 and older. 

 

Data for the study came from the 1992 National Longitudinal Epidemiologic Survey conducted by the National Institute on Alcohol Abuse and Alcoholism.  Respondents in this national probability survey were asked whether they had ever driven after having too much to drink, whether they had ever had a motor vehicle accident after having too much to drink, and whether either of these events happened in the last 12 months.  They were also asked how old they were when they first started drinking.

 

The study revealed that adults who started drinking at age 14 were three times more likely to report driving after drinking too much ever in their lives than those who began drinking after age 21.  Crashes were four times more likely for those who began drinking at age 14 when compared to those who began drinking after age 21 (see figure).

 

Even among  persons who never became alcohol dependent – i.e., alcoholics – those who began drinking by age 14 were significantly more likely than those who began drinking at age 21 or older to report being in a motor vehicle crash after drinking.

 

This study suggests that delaying the onset of alcohol use may result in lower rates of driving after drinking and fewer alcohol-related crashes.   The study highlights another reason to step up enforcement of the minimum 21-year-old purchase age and to expand educational and community efforts to delay the onset of drinking.

 

Hingson, R,  Heeren, T., Levenson, S.,  Jamanka, A, and Voas, R.  Age of Drinking Onset, Driving After Drinking, and Involvement in Alcohol-Related Motor Vehicle Crashes.  DOT HS 809.  Springfield, VA:  National Technical Information Service, 2001

 

 

 

  • Adults who started drinking by age 14 were three times more likely to report driving after drinking too much
  • Crashes were four times more likely for those who began drinking at age 14.
  • Delaying the onset of alcohol use may result in lower rates of driving after drinking and fewer alcohol-related crashes

  •  

     

    This document was supported by the Office of Juvenile Justice and Delinquency Prevention, in conjunction with its Enforcing Underage Drinking Laws program.  The opinions in this document do not necessarily reflect the official position of the US Department of Justice.

     

    Using Alcohol Policy to Reduce Underage Drinking:  Strategies
    that Work

     

    The Underage Drinking Enforcement Center

    Pacific Institute for Research and Evaluation

    Calverton, Maryland

     

    To a large extent, community environments determine whether and how much young people drink.1 This environment consists of the community’s alcohol-related norms and regulations and the availability of alcohol to young people (see figure).  Policymakers and concerned citizens can help to shape their community environment to support healthy choices about alcohol use.

     

    Controlling Alcohol Availability to Young People
    There is no better established principle in prevention than this:  If a community makes it more difficult for young people to obtain alcohol, underage drinking is reduced. In addition, because younger drinkers obtain alcohol from older people (friends, siblings, parents, and other adults), reducing the overall availability of alcohol in a community will reduce alcohol problems among young people.
     

        Enforcement of laws against underage drinking – Underage drinking laws are among our most important tools to reduce underage drinking,  and the better the enforcement, the  better the results.  Enforcement efforts are most efficient and effective when they focus on adults (retailers, parents, older friends) who provide alcohol to underage drinkers.   Nevertheless, enforcement aimed at young people themselves can send a message about community norms and may deter them from attempting to buy alcohol.

        Reducing overall availabilityReducing the overall availability of alcohol makes alcohol less convenient for young people to obtain. It also sends a message to young people that alcohol does not have to be the central feature of social life.  One important way to reduce the overall availability is to reduce the number of alcohol outlets relative to community size and population.  Communities can also prohibit alcohol outlets in areas that are frequented by young people, for example, near schools. Finally, communities can restrict alcohol availability at public events, such as fairs and festivals or in other public places, such as beaches and parks.  


    Controlling the Ways in Which Alcohol Is Advertised and Promoted
    Alcohol advertising and promotions are highly visible features of most community landscapes. The message often conveyed to young people is that drinking is expected, acceptable, and desirable. States and communities can reduce these messages through a variety of strategies:

  • Controlling the location and content of outdoor advertising
  • Prohibiting the distribution or sale to minors of alcohol promotional material (e.g., T-shirts).
  • Restricting or eliminating alcohol industry sponsorship of local community events.

  •  1 Regulatory Strategies for Preventing Youth Access to Alcohol:  Best Practices, Washington, D.C.: OJJDP, USDOJ. Presented at OJJDP National Leadership Conference, 7/11-14/99.

     

  • Community environments can exert powerful controls on drinking among young people
  • If a community makes it more difficult for young people to obtain alcohol, underage drinking is reduced
  • Alcohol advertising and promotions too often communicate to young people that drinking is expected, acceptable, and desirable.

  •  

     

    This document was supported by the National Highway Traffic Safety Administration, under the Department of Transportation. NHTSA provides a number of resources for the prevention of underage drinking, including the Community How To Guides On Underage Drinking Prevention.

     

    The Effects of Lowered Legal Blood Alcohol Limits for Young Drivers

     

    Alexander Wagenaar, Ph.D.*, Patrick O’Malley, Ph.D.**, and Colette LaFond, J.D.*

    *School of Public Health

    University of Minnesota

    Minneapolis, MN

    **Institute for Social Research

    University of Michigan

    Ann Arbor, Michigan

     

    Rates of alcohol-related traffic crashes in the United States have declined significantly in the past 2 decades, among both adults and teen­agers.  In ad­dition to efforts aimed at controlling driving while intoxicated among all drivers, several initiatives have specifically targeted teenaged drivers.  The most successful of these was raising the legal drink­ing age to 21.  Another important effort to reduce traffic crashes among young people was the enactment of laws that reduced the allowable blood alcohol concen­tration (BAC) for teenaged drivers to very low lim­its.  These laws are often referred to as “zero BAC” or “zero tolerance laws.”  In 1995, Congress passed legislation providing that any state not enact­ing a BAC limit of 0.02 or less for young drivers would lose 5% of its federal highway funds for that year and 10% each subsequent year.


    The study described here examined the effects of zero BAC laws in 30 states. The study was based on data collected from high school seniors across the United States as part of the Monitoring the Future project.1The results are shown in the figure.  Enactment of the zero BAC laws resulted in significant reductions in driving after drinking among young people.  The number of incidents of driving after any drinking in the two weeks before the survey dropped by more than 400 incidents (19%), and driving after five or more drinks dropped by more than 300 incidents (23%).


    Although zero tolerance laws are clearly effective in reducing impaired driving among young people, these laws are generally not well enforced, and many young people are not even aware of them.  Research shows that a public information campaign can increase the deterrent effect of zero BAC laws.  In short, improved enforcement and education efforts could substantially increase the beneficial effects of the laws.


    Wagenaar, A, O’Malley, P, and LaFond, C. Effects of lowered legal blood alcohol limits for young drivers:  Effects on drinking, driving, and driving after drinking behaviors in 30 states.  American Journal of Public Health 91(5):801-804, 2001.

     

     1 Monitoring the Future has been collecting nationally representative data on each high school senior class since 1975. The sample size for the study was approximately 5,000 students surveyed before the zero BAC laws and 5,000 students surveyed after the laws took effect. – See Johnson, L.D., O’Malley, P.M., and Bachman, J.G.  Monitoring the Future:  National Survey Results on Drug Use, 1975-2000.  Bethesda, MD:  National Institute on Drug Abuse, 2001.

     

  • Zero BAC laws reduced the allowable blood alcohol concen­tration (BAC) for teenaged drivers to 0.02 or lower
  • Enactment of zero BAC laws has resulted in significant reductions in driving after drinking among teens
  • Improved education and enforcement efforts could substantially increase the beneficial effects of zero BAC laws

  •  

     

    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) funded the research described in the following summary.  NIAAA funds more than 90 percent of the alcohol abuse and addiction (alcoholism) research in the United States.

     

    Parental Supervision And Teen Drinking

     

    Kenneth Beck1, Teresa Shattuck1, Denise Haynie2,  Aria Davis Crump1, and Bruce Simmons-Morton2

    1Department of Public and Community Health Education, University of Maryland, College Park

    2 Prevention Research Branch, Division of Epidemiology Statistics and Prevention Research, National Institute of Child Health and Human Development

     

    It is widely suggested that close parental supervision may reduce adolescent alcohol use.  The current study assessed associations between parent’s monitoring strategies and self-reported drinking behaviors of their adolescent children.  Interviews were conducted in a random sample of households in Maryland.  Households were eligible if a parent and at least one adolescent aged 14 to 19 resided in the home 2 weeks or more per month.  A total of 454 matched parent-adolescent pairs provided data for the survey, with a response rate of about 60 percent.


    Monitoring was measured by six questions that asked how often the parent:  1) monitors with whom their teen spends free time, 2) monitors how the teen spends free time, 3) sets a time when the teen is expected home, 4) monitors when the teen comes home, 5) determines if other parents are present at teen parties, and 6) supervises teen parties given in their homes. 

     

    For each item, parents were classified as either those who always monitor or those who monitor less than always.  Teens were categorized as “drinkers” if they reported any alcohol use in the past 12 months.

     

    The figure presents the relationship between parents’ supervision strategies and their teens’ drinking behaviors.  In all cases, drinking teens are more likely to have parents who do not always supervise them.  The strategy, “determines if other parents are present at parties,” significantly discriminated between drinkers and non-drinkers.

     

    Because the study was conducted at a single point in time,  it is not possible to determine whether parental supervision and youth drinking are causally related.  In addition, the low response rate indicates that truly dysfunctional families or parents reluctant to reveal their parenting practices may have been missed.  Nevertheless, the study strongly suggests that improving parental monitoring through parent education, support groups, and communication networks can reduce teen drinking.

     

     

    1 Beck, K., Shattuck, T., Haynie, D., Crump, A., and Simmons-Morton, B.  Associations between parent awareness, monitoring, enforcement and adolescent involvement with alcohol.  Health Education and Research:  Theory and Practice, 14(6):765-775, 1999.

     

     

  • It is widely suggested that close parental supervision may reduce adolescent alcohol use.
  • Phone interviews with parent-teen pairs found a relationship between parental monitoring practices and their teens’ drinking
          behaviors.
  • The study strongly suggests that improving parental monitoring through parent education, support groups, and communication
          networks can reduce teen drinking.

  •  

     

    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) funded the research described in the following summary.  NIAAA funds more than 90 percent of the alcohol abuse and addiction (alcoholism) research in the United States.

     

    Drinking and Related Problems: Sex and Race/Ethnicity

     

    Eleanor Z. Hanna1, Hsiao-ye Yi2, Mary Dufour1, and Christine Whitmore2

    1National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism

    Division of Biometry and Epidemiology

    2Alcohol Epidemiology Data System, CSR Inc.

     

    It is commonly assumed that, like their adult counterparts, boys drink more than girls and white adolescents drink more than members of other racial/ethnic groups.  This study examined sex and racial/ethnic differences in drinking and related problems using data from the 1997 Youth Risk Behavior Survey (YRBS), a nationally representative survey of ninth grade girls and boys attending schools in the United States.  Blacks and Hispanics are oversampled in order to allow analysis by race.  

     

    The study found similar rates of current drinking for boys and girls.  The study also compared the actual number of drinkers in each racial/ethnic group with the expected numbers given each group’s proportion in the general population.  As seen in the table, fewer Blacks, more Hispanic girls, and more boys in the “other” category are current drinkers compared to their proportions in the general population.

     

    The study also related current drinking to a variety of risk behaviors (e.g., driving after drinking, fighting).  Among current drinkers, Blacks, Hispanics, and members of “other” non-white racial/ethnic groups report higher rates of drinking-related risky behavior than do whites.  Higher socioeconomic status (indexed by mother’s education level) is associated with reductions in risk behavior.

     

    The results suggest that prevention planners should not assume that girls and non-white adolescents are at lower risk for drinking and related problems.  The drinking patterns of Hispanic girls, in particular, contradict this assumption.   The study also supports the hypothesis that Blacks and Hispanics, because they tend to be concentrated in areas associated with risk factors for drinking (e.g., poverty, billboard advertising, greater numbers of off-premise sales establishments) may experience a greater number of alcohol-related problems than whites.

       

    Hanna, E., Hsiao-ye, Y., DuFour, M., and Whitmore, C.  Risky Behavior by Sex and Race Among Currently Drinking Ninth Graders in the United States:  Results from the 1997 Youth Risk Behavior Survey (YRBS).  Poster presented at the 23rd Annual Scientific Meeting of the Research Society on Alcoholism, June 24-29, 2000, Denver, Co. 

     

    1 Wallace JM. The social ecology of addiction: race, risk, and resilience. Pediatrics, 103:1122-1127, 1999

     

      

  • Contrary to popular belief, ninth grade girls drink at rates similar to rates for boys
  • Black boys and girls drink at significantly lower rates than expected from their proportions in the general population
  • Boys in the “other” category and Hispanic girls drink at rates significantly higher than expected from their proportions in the general
          population
  • Among current drinkers, Blacks, Hispanics, and members of “other” non-white racial/ethnic groups report higher rates of drinking-
          related risky behavior than do whites.

  •  

     

    The National Institute on Alcohol Abuse and Alcoholism (NIAAA) funded the research described in the following summary.  NIAAA funds more than 90 percent of the alcohol abuse and addiction (alcoholism) research in the United States.

     

    Changes in Brain Activity in Alcohol-Dependent Young Women

     

    Susan F. Tapert, Gregory G. Brown, Sandra S. Kinderman, Eric H. Cheung, Lawrence R. Frank, and Sandra A. Brown.

    VA San Diego Health System and the
    University of California at San Diego


    Imaging studies of alcohol dependent adults have revealed a number of brain abnormalities.  However, it has been unclear when in the course of alcohol dependence or at what age such abnormalities appear.  The study reported here sought to reveal possible changes in the brains of alcohol dependent young women that might underlie the deficits in cognitive functioning observed in other studies of young drinkers.1 Young women were chosen for this study because other research has suggested heightened sensitivity of the female brain to alcohol effects.

     

    Participants were 10 women with histories of alcohol depen­dence and 10 healthy controls, all between the ages of 18 and 25.  In the 3 months before data collection, the alcohol dependent women were primarily weekend binge drinkers.  Seven of the ten met DSM-IV criteria for current alcohol dependence, and three had been abstinent for 6 months or longer.

     

    After a minimum of 72 hours of abstinence from alcohol, functional magnetic resonance imaging (fMRI) data were collected while participants engaged in a spatial working memory task (memory for the position of objects in space).  Compared to controls, the alcohol-dependent young women showed decreased activity in the areas of the brain associated with memory.  These decreases were most pronounced in young women who had experienced alcohol withdrawal symptoms at some time in the past.

     

    This study suggests alcohol dependency in young women is associated with decreases in brain activity.   The study also suggests that heavy drinking leading to withdrawal poses particular threats to brain functioning.  The researchers stress the need for similar studies with younger adolescents in order to determine how early drinking-related brain consequences can be detected.

     

    Tapert, S., Brown, G., Kinderman, S., Cheung, E., Frank, L., and Brown., S.  fMRI measurement of brain dysfunction in alcohol-dependent young women.  Alcoholism: Clinical and Experimental Research, 25(2):236-245, 2001.

     

    1 See Science, Kids, And Alcohol - Heavy Alcohol Use and Nervous System Development.

     

     

  • Evidence is increasing that alcohol-dependent young people experience deficits in cognitive functioning
  • Functional magnetic resonance imaging (fMRI) revealed changes in brain functioning that may underlies these deficits
  • Heavy drinking patterns leading to withdrawal pose particular threats to brain functioning in young women.

  •  

     

    This document was supported by the Office of Juvenile Justice and Delinquency Prevention, in conjunction with its Enforcing Underage Drinking Laws program.  The opinions in this document do not necessarily reflect the official position of the US Department of Justice.

     

    Enforcement of Underage Drinking Laws:  Strategies that Work


    The Underage Drinking Enforcement Center

    Pacific Institute for Research and Evaluation

    Calverton, Maryland


    Laws establishing 21 as the minimum purchase age for alcohol (adopted in all states by 1988) have been shown to be extremely effective in reducing underage alcohol consumption and its consequences1. National Highway Safety Trafic Association (NHTSA). 2007. Traffic Safety Facts 2006— Young Drivers. Washington, DC: NHTSA, National Center for Statistics and Analysis. 2 ,3 


    Despite the effectiveness of 21-year-old purchase age laws, more vigorous enforcement would further reduce underage drinking and save even more young lives.  Evaluations have shown repeatedly that when the following techniques are applied, rates of sales to minors drop dramatically:


    Enforcement aimed at retailers
    Because there are many fewer sellers of alcohol than there are purchasers, strategies aimed at retailers are efficient.  They are also very successful in reducing sales of alcohol to minors. Enforcement aimed at retailers includes the following key elements:

  • Vigorous use of compliance checks
  • Applying appropriate sanctions to merchants who sell to underage individuals
  • Educating merchants regarding their responsibilities under the law
  • Developing media coverage and community support for enforcement.


  • Enforcement aimed at other sources of alcohol
    Young people obtain alcohol from many sources, including older friends and siblings, adults who agree to buy for them, and even parents. Some strategies for reducing these sources of alcohol include:

  • Enacting keg registration laws that make the purchasers of kegs of beer responsible if minors are served from
        those kegs.
  • Enforcing laws that prohibit buying alcohol for minors and citing adults who purchase for them
  • Holding adults responsible if alcohol is served to minors in their homes
  • Conducting enforcement campaigns to prevent or safely disperse parties where minors are drinking.


  • Enforcement aimed at young people
    Little research is available demonstrating the effectiveness of enforcement aimed at young people.  However, enforcement programs, such as “Cops in Shops,” send a message about community norms and may deter young people from attempting to buy alcohol. Such youth only-approaches should be used in combination with other proven strategies.

     

    1 O’Malley, P., and Wagenaar, A. Effects of minimum drinking age laws on alcohol use, related behaviors, and traffic crash involvement among American youth 1976-1987. Journal of Studies on Alcohol, 4:807-818, 1991

    2 National Highway Safety Traffic Association. 2006. Traffic Safety Facts 2005: Young Drivers. DOT HS Report No. 810 630. Washington, DC: National Center for Statistics and Analysis.

    3 Parker, M., and Rebhun, L. Alcohol and Homicide: A Deadly combination of Two American Traditions. Albany, NY: State University of New York Press, 1995.

    4 Mosher, J.   The merchants, not the customers: Resisting the alcohol and tobacco industries’ strategy to blame young people for illegal alcohol and tobacco sales. Journal of Public Health Policy, 16(4):412-432, 1995.

     

     

  • Minimum purchase age laws have been effective in reducing drinking and fatalities and can be even more effective with aggressive
         enforcement
  • Vigorous enforcement of laws prohibiting retail sales of alcohol to minors decreases these sales dramatically
  • Enforcement aimed at retailers is more efficient and effective than enforcement aimed at purchasers

  •  

      Abstracted for the Leadership to Keep Children Alcohol Free

     

    Drinking and Domestic Violence


    Nationally representative surveys indicate that one in six couples experiences an incident of partner-to-partner violence each year. Thus, domestic violence constitutes a significant public health concern. Researchers have long noted a relationship between heavy alcohol consumption and domestic violence. Some have suggested that problem alcohol use and domestic violence often occur together because the same personality characteristics put people at risk for both behaviors.Others have suggested that heavy alcohol consumption contributes to unhappy and conflict-ridden domestic environments, which in turn lead to violence. However, recent studies suggest that the relationship between problem drinking and domestic violence is causal and direct – that is, alcohol consumption directly contributes to the frequency and severity of domestic violence.


    The first study 1 examined the day-to-day occurrence of drinking and partner violence among couples who had experienced at least one episode of male-to-female aggression in the previous year. Data on drinking and aggression were gathered over a 15-month period through the use of diaries kept by both partners and quarterly interviews with each partner. The odds of male-to-female violence increased 8- to 11-fold on drinking days.


    The second study 2 followed 366 newlywed couples over a 1-year period. Assessments at the time of marriage measured factors associated with marital violence. Interviews conducted at the 1-year anniversary revealed strong associations between husbands who drank and episodes of physical violence (although not verbal aggression). In conclusion, the results of the present study strongly support an association between husband drinking and the occurrence of marital aggression, but not between wife drinking and the occurrence of aggression.


    In both studies, the results were sustained even when other factors that might cause both drinking and violence were statistically controlled. Thus, both studies suggest a direct, causal relationship between male drinking and male-to-female partner violence. These findings suggest that strategies that reduce the alcohol consumption of male partners (including both prevention and treatment) can directly contribute to reductions in domestic violence.

  • Approximately one in four children, is exposed to family alcoholism or addiction, or alcohol abuse, some time before the age of 18.3
  • Two-thirds of victims who suffered violence by an intimate (a current or former spouse, boyfriend, or girlfriend) reported that
          alcohol had been a factor.4
  • Among spouse victims, 3 out of 4 incidents were reported to have involved an offender who had been drinking.4
  •  1 Fals-Stewart, W. The occurrence of partner physical aggression on days of alcohol consumption: A longitudinal diary study. Journal of Consulting and Clinical Psychology, 71(1):41-52, 2003.

    2 Leonard, K., and Quigley, B.Drinking and marital aggression in newlyweds: An event-based analysis and the occurrence of husband marital aggression. Journal of Studies on Alcohol, 60:537-535, 1999.

    3 Grant BF. Estimates of US children exposed to alcohol abuse and dependence in the family. American Journal of Public Health 90(1): 112-115, 2000.

    4 U.S. Department of Justice. Bureau of Justice Statistics. National Crime Victimization Survey 2002. http://www.ojp.usdoj.gov/bjs/cvict_c.htm (accessed online August 28, 2003).